11th Japanese Safety Pharmacology Society Annual Meeting Program (as of February 20, 2020)

Day 1: Friday, Feb. 28

8:30 〜 18:30 Poster Sessions <Kamijo Memorial Hall 4F, Akamatsu>
8:30 Doors open
10:00 〜 10:10 Opening remark Tomoharu Osada President of 11th Annual Meeting
10:10 〜 11:55 Symposium I: Cardiovascular System <Kamijo Memorial Hall 1F, Kamijo Hall>
  1. Mechanistic insight in drug-induced arrhythmogenicity: CAST-type arrhythmogenicity and LQT-type arrhythmogenicity
    Tetsushi Furukawa (Department of Bio-informational Pharmacology, Tokyo Medical and Dental University)
  2. Molecular mechanism underlying cardiac early afterdepolarization induced by IKr and IKs suppression
    Mitsuhiko Yamada (Molecular Pharmacology, Shinshu University School of Medicine Graduate School of Medicine)
  3. Genetic Predispositions for Sudden Death in Brugata Syndrome Deciphered by Comprehensive Analyses Using Functional Evaluation and Whole-Exome Sequencing
    Naomasa Makita (Research Institute, National Cerebral and Cardiovascular Center)
11:55 ~ 12:15 Coffee Break
12:15 〜 13:15 Luncheon Seminar 1<Kamijo Memorial Hall 1F, Kamijo Hall>
  • Improvement of Human Induced Pluripotent Stem Cells for Functional Assessment, Disease Models and Cardio-Oncology
    Sponsored by Scrum Inc. / ACEA Biosciences, Inc.
13:15 ~ 13:30 Coffee Break
13:30 〜 14:00 Flash talk(1-minute BOOTH presentation) <Kamijo Memorial Hall 1F, Kamijo Hall>
14:00 ~ 14:15 Break
14:15 〜 14:50 Invited Lecture I <Kamijo Memorial Hall 1F, Kamijo Hall>
  1. NOAEL in safety pharmacology: Yes or No?
    Tomas Mow (Novo Nordisk A/S, 2020 SPS acting president)
14:50 〜 15:20 Coffee Break
15:20 ~ 16:10 Flash Talk (1-minute POSTER presentation)<Kamijo Memorial Hall 1F, Kamijo Hall>
16:10 ~ 16:40 Break
16:40 〜 18:10 Poster Presentation Core Time (odd numbers) <Kamijo Memorial Hall 4F, Akamatsu>

18:30 〜 20:30 Banquet Party   Banquet Party has been canceled

Day 2: Saturday, Feb. 29

8:00 〜 15:30 Poster Sessions  <Kamijo Memorial Hall 4F, Akamatsu>
8:00 Doors open
8:30 〜 10:15 Symposium II: Central Nervous System <Kamijo Memorial Hall 1F, Kamijo Hall>
  1. The impact of Safety Pharmacology studies on the development of Siponimod, drug to treat multiple sclerosis
    Martin Traebert (Novartis Pharma AG, President of SPS 2019)
  2. Unveiling immune-brain metabolic interaction by mass spectrometry
    Yuki Sugiura (Department of Biochemistry, School of Medicine, Keio University)
  3. NCNP biobank: From biomarker development to post-marketing study
    Kotaro Hattori (Translational Medical Center, National Center of Neurology and Psychiatry)
10:15 ~ 10:30 Break
10:30 〜 12:15 Special Lecture Artificial Intelligence  <Kamijo Memorial Hall 1F, Kamijo Hall>
    1. Challenges of Artificial Intelligence to Change the Real World
      Naohiko Uramoto (Mitsubishi Chemical Holdings Corporation)
    2. Application of Deep Learning for Drug Discovery
      Ryuichiro Ishitani (Preferred Networks, Inc.)
    3. Prospects for the present and future of artificial intelligence in cardiovascular imaging
      Kenya Kusunose (Cardiovascular Medicine, Faculty of Medicine, Tokushima University)
12:15 ~ 12:30 Break
12:30 〜 13:30 Luncheon Seminar II  <Kamijo Memorial Hall 1F, Kamijo Hall>
  1. Toxicity Signature Analysis – Translational Insights with the Speed and Ease of in vitro Evaluation
  2. Integrated Cardiac Proarrhythmic Risk Assessment Under The CiPA Initiative

   Sponsored by Eurofins Discovery

13:30 ~ 14:00 Break
14:00 〜 15:15 Poster Presentation Core Time (even numbers) <Kamijo Memorial Hall 4F, Akamatsu>
15:15 ~ 15:30 Break 
15:30 〜 16:40 Symposium III: Case studies of drug development
  1. Preclinical and clinical profiles of a humanized IL-23 mAb, risankizumab (Skyrizi®)
    Hirotaka Tokunaga (AbbVie GK)
  2. Challenge of the iD3 booster
    Nobuyoshi Chiba (Japan Agency of Medical Research and Development (AMED))
16:40 〜 17:15 Closing
      JSPS Award Ceremony Tomoharu Osada (Selection Chairman)
      Closing Remarks Yoshiki Deguchi (President of 12th Annual Meeting)

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